Platelet-Rich Plasma

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Platelet-Rich Plasma for Patellar Tendinopathy: A Randomized Controlled Trial of Leukocyte-Rich PRP or Leukocyte-Poor PRP Versus Saline


Background:

A small number of randomized controlled trials have found ultrasound-guided injection of platelet-rich plasma (PRP) to be no more effective than saline for several tendinopathies; limited information exists for patellar tendinopathy. In addition, different PRP formulations that produce varying concentrations of leukocytes have not been directly compared for patellar tendinopathy.

Purpose/Hypothesis:

To determine if a single […]

Platelet-Rich Plasma for Patellar Tendinopathy: A Randomized Controlled Trial of Leukocyte-Rich PRP or Leukocyte-Poor PRP Versus Saline

Use of Platelet-Rich Plasma Immediately After an Injury Did Not Improve Ligament Healing, and Increasing Platelet Concentrations Was Detrimental in an In Vivo Animal Model

Background: Limited information in basic science and clinical trials exists to determine if ligament healing may be accelerated with the use of biological adjuvants, such as platelet-rich plasma (PRP). However, there has been widespread acceptance of PRP for use in clinical practice, despite an inadequate understanding of its biological […]

Use of Platelet-Rich Plasma Immediately After an Injury Did Not Improve Ligament Healing, and Increasing Platelet Concentrations Was Detrimental in an In Vivo Animal Model

Minimum Information for Studies Evaluating Biologics in Orthopaedics (MIBO): Platelet-Rich Plasma and Mesenchymal Stem Cells

It is not yet clear whether current and emerging biologic strategies to treat musculoskeletal injuries will provide tangible benefits to patients . Platelet-rich plasma (PRP) is used widely despite a lack of evidence supporting its efficacy. Enthusiasm for mesenchymal stem cell (MSC)-based therapies is reflected by the prodigious number […]

Minimum Information for Studies Evaluating Biologics in Orthopaedics (MIBO): Platelet-Rich Plasma and Mesenchymal Stem Cells

Biologic Approaches for the Treatment of Partial Tears of the Anterior Cruciate Ligament

The anterior cruciate ligament (ACL) is one of the most studied structures of the human musculoskeletal system, being the subject of many anatomic and biomechanical studies. While treatment options for complete ruptures of the ACL are well studied, partial ACL tears remain more nebulous in their postinjury treatment course. Partial ACL tears were first described […]

Biologic Approaches for the Treatment of Partial Tears of the Anterior Cruciate Ligament
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