Refrigerated Osteoarticular Allografts to Treat Articular Cartilage Defects of the Femoral Condyles

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JOURNAL OF BONE AND JOINT SURGERY 2009

Because of concerns about infections with the use of fresh osteoarticular allografts, osteoarticular allografts are currently stored hypothermically for a minimum of fourteen days to allow for serologic and microbiologic testing prior to implantation. Refrigerated osteoarticular allograft transplants are often used to treat symptomatic chondral and osteochondral defects in young, active patients. Chondrocyte viability has been shown to decrease substantially when allografts are stored for longer than twenty-eight days.

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