Biologics

Evidence for the use of cell-based therapy for the treatment of osteonecrosis of the femoral head: A Systematic Review of the literature

Cell-therapy has been promoted among the therapeutic arsenal that can aid in 6 bone formation and remodeling, in early stages of osteonecrosis of the femoral head (ONFH). The purpose of this systematic review was to assess the evidence supporting the: (1)clinical efficacy; (2)structural modifying effect; as evaluated radiographically (3) revision rates; and (4)safety of […]

Evidence for the use of cell-based therapy for the treatment of osteonecrosis of the femoral head: A Systematic Review of the literature

Bone Marrow Aspirate Concentrate Harvesting and Processing Technique

Bone marrow obtained by iliac crest aspiration is a common source for harvesting mesenchymal stem cells, other progenitor cells, and associated cytokine/ growth factors. Because the use of bone marrow aspirate concentrate (BMAC) is currently approved by the United States Food and Drug Administration, it represents one of the […]

Bone Marrow Aspirate Concentrate Harvesting and Processing Technique

Outcomes After Biologically Augmented Isolated Meniscal Repair With Marrow Venting Are Comparable With Those After Meniscal Repair With Concomitant Anterior Cruciate Ligament Reconstruction

2017 AJSM

Meniscal repair procedures are increasingly performed because of an enhanced understanding of the long-term deleterious consequences of meniscectomy, the benefits of meniscal preservation, and the improved techniques and devices available for meniscal repair. While meniscal repair has demonstrated a higher reoperation rate than meniscectomy, recent studies have reported […]

Outcomes After Biologically Augmented Isolated Meniscal Repair With Marrow Venting Are Comparable With Those After Meniscal Repair With Concomitant Anterior Cruciate Ligament Reconstruction

Biologic Approaches for the Treatment of Partial Tears of the Anterior Cruciate Ligament

The anterior cruciate ligament (ACL) is one of the most studied structures of the human musculoskeletal system, being the subject of many anatomic and biomechanical studies. While treatment options for complete ruptures of the ACL are well studied, partial ACL tears remain more nebulous in their postinjury treatment course. Partial ACL tears were first described […]

Biologic Approaches for the Treatment of Partial Tears of the Anterior Cruciate Ligament

AAOS Research Symposium Updates and Consensus: Biologic Treatment of Orthopaedic Injuries

2016 AAOS

Strategies that seek to enhance musculoskeletal tissue regeneration and repair by modulating the biologic microenvironment at the site of injury have considerable therapeutic potential. Current and emerging biologic approaches include the use of growth factors, platelet-rich plasma, stem cell therapy, and scaffolds. The American Academy of Orthopaedic […]

AAOS Research Symposium Updates and Consensus: Biologic Treatment of Orthopaedic Injuries
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